Tuesday, September 13, 2011

Is taurine mimicing this inactivation…

Genetic alterations of metabolic enzymes profoundly impact fat levels in C. elegans. For example, RNAi inactivation of key glycolic and gluconeogenic genes such as GAPDH, an insulin-regulated glycolytic enzyme, and PEPCK, a regulated enzyme of gluconeogenesis and glyceroneogenesis, cause fat reduction (Ashrafi et al., 2003).

Obesity and the regulation of fat metabolism - WormBook - NCBI Bookshelf

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